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Exendin-4 had anti-inflammatory properties by activating adenylate cyclase (cAMP) in macrophages, which inhibited the expression of TNF- (tumor necrosis factor ) and MCP-1inflammatory and atherogenic mediators
It is synthesized from three amino acids: glutamate, cysteine, and glycine
It highlights emerging evidence of the interconnectedness among iron overload, senescence, and fibrosis, examining their potential crosstalk and collective role in disease progression (Fig
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