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Discussion: Overall, this study highlights the importance of collecting proper metabolic expression (specifically drug uptake rate, CYP450 enzymatic activity, and glutathione quantity) to ensure an accurate estimation of patient damage

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Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (Liraglutide Effect and Action in Diabetes)-2 study