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By doing so, it can specifically target the tissues it needs to without affecting other areas
The impact of energy deprivation on the signaling pathways of erythrocytes was later disclosed in a mechanistic study: here, the authors demonstrated that removal of extracellular glucose and blockade of glycolysis by 2-deoxyglucose leads to fast depletion of cellular ATP
However, repeated use of DEET in very high concentrations can lead to toxic encephalopathy with severe neurological symptoms including seizures, tremors and slurred speech
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