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These metabolites were grouped into lipid-metabolism molecules such as cholestenone, cholesterol, 3 methyladipate pimelate and X2 hydroxymyristic acid, active metabolites and neurotransmitters such as valeric/isovaleric acid, azelate, azelaic acid, C20:4 carnitine, undecanedioic acid, vitamin related metabolites such as the pyridoxamine and nucleotide/nucleoside metabolites such as the deoxyinosine
Most people tolerate them well, with minimal side effects
van der Velden J, Asselbergs FW, Bakkers J et al (2022) Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored
Aortic dissection occurs when there is a break in the lining of the artery wall, allowing blood to enter and form a hematoma, further stripping the intima and media of the aorta
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