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2024ZD0521101]
ChaC2 induces mitochondrial apoptosis and autophagy via UPR, serving a pivotal role as a tumor suppressor gene in the onset, proliferation and metastasis of gastric and colorectal cancer (79)
Notably, all patients had previously been treated with pentosan polysulfate, which is currently the only FDA approved treatment for interstitial cystitis, and had not responded
In addition, supplementing the raw materials (cysteine, glycine, glutamate, and selenium) for synthesizing GSH or GPX to achieve an elevated GSH system in the myocardium is another feasible strategy
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