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Protocols come from research literature, clinical experience, and community knowledge
Common side effects include nausea, vomiting, and diarrhoea, usually mild and improving over time with dose titration
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Anvisa launched a formal accelerated review program in August 2025 Invitation Notice CFP 12/2025 at the request of Brazil's Ministry of Health, specifically to fast-track GLP-1 drug reviews in advance of the semaglutide patent expiry
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