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This is consistent with findings from the SUSTAIN-6 and PIONEER trials, which reported reductions in major adverse cardiovascular events (MACE) with semaglutide use
Remove the outer and inner needle cap, and perform a flow check of the pen as per the leaflet instructions (this only needs to be done when using the pen for the first time)
and Livon Labs, and conducted under the Declaration of Helsinki (2013) and ICH E6(R2) Good Clinical Practice guidelines
Semaglutide was originally developed for type 2 diabetes, where it produces HbA1c reductions of 1.52.0 percentage points
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