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Set Y (756 genes) was altered by GLP-1R agonism in both the control and the ethanol diet, and also regulated by ethanol in the absence of a GLP-1R agonist (Supplementary Fig
GLP1R , the GLP-1 receptor gene these compounds target, is joined by FTO (the fat-mass and obesity-associated gene), MC4R (a melanocortin receptor central to satiety and energy balance), and TCF7L2 (a transcription factor tied to glucose homeostasis and GLP-1 secretion)
( N ) MM%
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