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Vitamin D supplementation: a potential approach for coronavirus/COVID-19 therapeutics

While single-cell metabolomics is a powerful tool for profiling individual cell metabolism in tissues, the technically demanding isolation and preparation of tissue samples for metabolic analysis without introducing artifacts or altering the native metabolic state remain significant challenges

Given that AA-derived eicosanoids (prostaglandins, thromboxanes, and leukotrienes) play divergent roles in vasoconstriction, inflammation, and platelet aggregation [173], the roles of various LS-induced AA metabolites in modulating EC function and atherogenesis require further investigation

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