According to the National Institute on Drug Abuse, approximately half of individuals with a substance use disorder also experience a co-occurring mental health condition, including depression, anxiety, PTSD, bipolar disorder, and personality disorders
Patients with a second underlying condition (such as a second rheumatological condition), were not helped as much by the programme, nor did their blood markers show such a big response
Evidence-based autoimmune disease treatments include disease-modifying antirheumatic drugs (DMARDs) like methotrexate, biologic agents targeting specific inflammatory pathways (TNF- inhibitors, IL-6 inhibitors), JAK inhibitors, corticosteroids for acute flares, and immunomodulators
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