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Deelchand, PhD, Center for Magnetic Resonance Research (CMRR), Minneapolis, MN
Oxidation of disulfide bonds of Pt GSTF8 Disulfide bonds between C13 of purified apo- Pt GSTF8 variants and GSH were formed by incubating 20 M Pt GSTF8 with 0 mM or 1 mM GSSG in the presence of 200 M GSH in 10 mM MOPSO, pH 6.45 for 2 h at 30 C, 800 rpm using a 3 mm shaking diameter
A patient weighing over 300 pounds with type 2 diabetes may show better outcomes starting at 5 mg compared to a 180-pound individual seeking weight loss alone
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