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GLP-1s have been used for diabetes treatment since 2005 and for weight management since 2014
Michael White, head of pharmacy practice at the University of Connecticut, notes adverse skin reactions in roughly 10 to 15% of users
It remains a research compound
As monotherapy , a multicentre, randomised, double-blind, placebo-controlled and active-controlled Phase 2 dose-finding trial enrolled 706 adults with overweight or obesity (without diabetes) to once-weekly subcutaneous cagrilintide across doses of 0.3 to 4.5 mg over 26 weeks
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