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The biofilm ECM contains polysaccharides, such as mannan-glucan complexes, extracellular DNA, proteins, and extracellular vesicle cargo, that together impede fungal penetration and may sequester antifungals, leading to reduced effective concentration at the cell surface (Roy and Gow, 2023
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NAC, N-acetyl-L-cysteine
Typically, a B12 shot is administered in the upper buttocks, but some nurses will also use the shoulder
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