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While not a direct predictor of semaglutide itching, variants in genes affecting inflammation (like those controlling cytokine release) can flag higher risk, helping your PlexusDx provider personalize your compound and dosing strategy to minimize dermatological side effects

To ensure temporality between GLP-1 RA use and SUD onset, we established the observation window from January 1, 2005 (the year of initial GLP-1 RA approval) to February 24, 2025, based on the most recent data available from the AoU dataset

Finally, we examined the effects of three GSSG-enhancing chemicals on IKK- glutathionylation (IKK--SSG adduct formation) by IP and immunoblotting