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For the L-GSH supplementation group, there was a significant decrease in the levels of oxidized GSH in PBMCs ( Figure 4J ) and RBCs ( Figure 4K ), but not in plasma ( Figure 4I )

But the effectiveness of glutathione for skin lightening depends on several factors, including skin types, existing pigmentation, dosage, method of administration, lifestyle factors, and individual skin biology

doi: 10.1371/journal.pone.0179538