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These GLP-1 receptor agonists can be categorized as either short-acting compounds, which provide short-lived receptor activation (such as exenatide and lixisenatide) or as long-acting compounds (for example albiglutide, dulaglutide, exenatide long-acting release, and liraglutide), which activate the GLP-1 receptor continuously at their recommended dose

First, in the system construction phase, the initial structure of the target molecule (such as a protein-ligand complex) must be determined, and environmental factors such as solvent molecules (e.g., water) and ions must be added

Determination of extracellular glutathione in rat brain by microdialysis and high-performance liquid chromatography with fluorescence detection