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WS-917 binds ABCB1, stimulates its ATPase activity, and reverses resistance by increasing intracellular paclitaxel by 730-fold, with low toxicity and synergy with CD8 + T-cell responses
Unlike prednisone, budesonide has a high first-pass metabolism
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The opposing effects of GIP and GLP-1 on lipogenesis and lipolysis, respectively, help maintain adipocytes in young and healthy state, fostering higher levels of adiponectin a key adipokine known for its potential antidiabetic, anti-inflammatory, and antiatherogenic properties (185)
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