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Increased toxicity of a pharmacologically active metabolite of irinotecan (SN38) has been described in patients suffering from Gilberts syndrome as UGT1A1 is the main enzyme responsible for the formation of the inactive SN38 glucuronide (Wasserman et al., 1997)
These natural levels may be depleted over time by stress, aging, and poor lifestyle choices, and can lead to more free radicals in the body
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TB-500 Solution turned yellow: A slight yellow tint is normal
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