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Apoptosis induces tissue injury and fibrosis in MASH and many other chronic liver injuries, 79 establishing a rationale for inhibiting apoptosis as a therapeutic strategy
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Gastric surgery, such as weight loss procedures, can also lead to vitamin B12 deficiency by reducing the number of cells needed to secrete stomach acid and intrinsic factor
In trials, tirzepatide showed it could help people lose up to 22.5% of their total body weight
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