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[6] These analyses are useful, but they are the weakest tier for a two-drug verdict: indirect comparisons inherit every difference between the underlying trials and cannot substitute for a randomised head-to-head

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Key mechanistic actions of GHK-Cu include: Enhancement of Antioxidant Enzyme Activity: GHK-Cu increases superoxide dismutase (SOD) and catalase activity in preclinical studies

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doi:10.1016/j.peptides.2025.171380

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