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The underlying mechanism of selective insulin resistance has not been established but several hypotheses have been suggested

For patients on concurrent antibiotic therapy, it is crucial to separate the probiotic and antibiotic doses by at least two hours to prevent a reduction in probiotic viability (128)

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Initially developed for type 2 diabetes, these agents are increasingly used for weight management, with landmark trials such as STEP and SELECT demonstrating double-digit weight loss and reduced risk of major cardiovascular events