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doi:10.1111/j.1432-1033.1982.tb05780.x

Binders are substances that may adsorb certain toxins within the gastrointestinal tract, potentially reducing reabsorption during enterohepatic recirculation and promoting fecal excretion

More is not necessarily better, and extremely high doses are not required for effectiveness

A total of 50 participants (men and women, 3560 years of age) with dry skin, skin moisture content of 49% or less, or crows feet greater than grade 3 were tested for 12 weeks in this double-blind, randomized, parallel, placebo-controlled study (equal numbers of subjects were in the APCP or placebo groups)