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Tetra-O-methyl nordihydroguaiaretic acid inhibits growth and induces death of leukemia cells independent of cdc2 and survivin

13b, Supplementary Table 9), indicating that the interactions between the C-terminal tyrosine and RAMP3 can compensate, in this peptide context, the reduced CTR ECD affinity derived from the P37Y substitution

For instance, macrophages differentiate into different subtypes, participate in synovial inflammatory responses, and exacerbate cartilage damage by releasing inflammatory mediators (such as IL-1,TNF-) and proteases (such as MMPs,ADAMTs) ( At the same time, the differentiation of immune cells is influenced by the joint microenvironment

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