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HDAC3 and HDAC11, for instance, regulate oxidative stress responses and A metabolism, whereas HDAC7 contributes to tau pathology by suppressing lysosomal biogenesis through transcription factor EB (TFEB) deacetylation and by enhancing inflammatory signaling via the IKKNF-B pathway 31
CRISPR-based gene editing systems The advancement of gene editing systems beyond Cas9, including Cas12, Cas13, and Cas14, has expanded the toolkit for precise genetic manipulation in tumor therapy, necessitating in-depth exploration of their unique mechanisms, advantages, and translational potentials [121]
And I wasn't the one suffering, but I know it was going to destroy her body for the rest of her life
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