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According to Mayo Clinic, gastrointestinal issues remain among the most commonly reported side effects, including nausea, vomiting, diarrhea, constipation, bloating and stomach discomfort
Persistent lumps or thickened areas (lipohypertrophy) indicate tissue changes from repeated injections in the same spot
Treatment was well tolerated
Verdict: Limited evidence overall DSIP has some preliminary human sleep data, but most broader claims remain unproven, and safety uncertainty is substantial [24][14]
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