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This matters because muscle tissue is metabolically active
This approach would be mainly focused on increasing GLP-1 levels rather than stimulating GIP because in these patients the responsiveness of their -cells to GIP action is decreased (Reference Nauck14)
Unlike many other peptides, BPC-157 works systemically, meaning its benefits extend beyond just the gastrointestinal tract
Given the established cardiovascular and kidney benefits of SGLT2is for T2DM patients with CVDs, those at high risk, and those with CKD, along with recent cohort studies demonstrating their ability to enhance survival, reduce cardiovascular events, and preserve graft function in kidney KTRs with DM, we conducted additional analyses incorporating SGLT2is [38,39,40,41,42]
