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Key Points Semaglutide starts at 0.25 mg weekly and increases slowly over months to help your body adjust and minimize side effects The maintenance dose is 2.4 mg weekly for Wegovy Your doctor can adjust the timing or your final dose based on how well your body responds to the medication and your weight loss results Starting semaglutide can feel overwhelming when you're facing questions about dosing, side effects, and realistic expectations

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The resulting symptom worsening is not deconditioning, it is cellular energy bankruptcy that rest cannot immediately resolve