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The bonds that give them their structure and function are fragile in ways that most pharmaceuticals arent, as a 2025 review in Protein & Peptide Letters on therapeutic peptide stability documented: heat and environmental exposure during storage and transit break down amino acid bonds, degrading the compound before it reaches the consumer

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Evidence indicates that StAR transiently localizes to the MAMs region, where it interacts with the OMM protein voltage-dependent anion channel 2 (VDAC2) to facilitate the precise delivery of cholesterol to the inner mitochondrial membrane