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This may involve adjusting both basal insulin and mealtime insulins or taking additional medications like metformin, SGLT-2 inhibitors, or GLP-1s

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SB: Data curation, Writing original draft, Writing review & editing, Conceptualization

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Worsening headaches after week 4 suggest inadequate metabolic adaptation or an unaddressed contributing factor

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Back Montesano, R, Schekman, R, Rothman, J, Perrelet, A (7 Jan 2020) 'In Memoriam: Leilo Orci, 1937-2019', Proceedings of the National Academy of Sciences , 117/1, 15-17

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