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It is rarely the first hormone discussed in the context of women's health, and its decline during the menopausal transition receives far less clinical attention than the fall in estrogen and progesterone
injection with 100 nmol kg 1 MK-801 ( n = 7 mice), 100 nmol kg 1 GLP-1 ( n = 8 mice), 100 nmol kg 1 GLP-1MK-801 ( n = 7 mice) or vehicle (isotonic saline, n = 8 mice) in lean mice
Elevated histone Kla enhances the expression of neuronal activity markers such as c-Fos, leading to reduced social behavior and increased anxiety
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