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4.1 Central nervous system effects GLP-1R is distributed throughout various regions in the brain, with the highest concentrations being found in the hippocampus and cerebral cortex, areas mainly responsible for cognitive function, memory improvement, and learning (10)
B12 is an essential vitamin that plays a role in red blood cell production, nerve function, and immune support
However, side effects such as nausea and muscle loss remained
While not specifically studied with tirzepatide, changes in appetite-regulating hormones that also influence sleep-wake regulation could hypothetically contribute to altered sleep quality during active weight loss phases
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