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Research published in obesity medicine shows that metabolic rate can decrease by 1015% after significant weight loss, meaning your body requires fewer calories at maintenance

More specifically, both RCTs with paired liver biopsies showed improvement in hepatic steatosis and inflammation, but not fibrosis, after treatment with liraglutide or semaglutide

Another study from Food Science & Nutrition found that Eriomin lemon fruit extract increased blood levels of GLP-1 but didn't help to decrease weight

Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability