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Data from 8 randomized controlled trials (6,361 participants) indicated that this level of weight loss could last as long as 3.5 years, although information on long-term safety remains limited
The FDA's decision to include this boxed warning reflects the agency's conservative approach to potential carcinogenic signals, even when human relevance is uncertain
Midlife women are a particularly important group here
However, the authors also said that further research is needed before scientists will know the best way to use it for cancer treatment or prevention
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