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The primary molecular target of the TB-500 fragment is monomeric G-actin: thymosin beta-4 is the most important intracellular G-actin-sequestering peptide and buffers the equilibrium between G- and F-actin, by which it regulates cytoskeletal dynamics, cell migration, angiogenesis and wound repair

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"Over half of the projects awarded during this cycle support drinking water and wastewater systems, critical for the health and safety of Colorado communities." In the San Luis Valley, several projects have been funded