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the magnitude of HbA1c change in this non-diabetic population was modest, as would be expected Fasting insulin levels decreased, indicating improved insulin sensitivity Triglyceride and lipid profiles showed favourable changes, which may reduce cardiometabolic risk Waist circumference was substantially reduced, reflecting a decrease in visceral (abdominal) adiposity These findings are particularly relevant given that excess visceral fat is strongly associated with type 2 diabetes, cardiovascular disease, and metabolic syndrome
Melanotan 2 is unapproved and carries documented safety concerns, and afamelanotide is a prescription drug for a specific disease neither is presented here as a cosmetic or self-administered protocol
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