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Treating environmental allergies For airborne allergens, such as pollen, dust, and mold spores, additional treatment options include: Treating allergies on the skin For allergic reactions that cause skin symptoms, including those associated with allergens found in animal saliva, poisonous plants, drugs, chemicals, and metals, additional treatment options include: topical corticosteroid creams or tablets moisturizing creams cold compresses Treating severe allergies People should speak to a professional if they have or suspect that they have severe or chronic allergies