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Besides, in ketogenic dietary interventions, FGF-21 reduces IL-1 secretion by macrophages, further alleviating systemic inflammation and metabolic dysfunction [256]
Progression from ductal carcinoma in situ to invasive breast cancer: molecular features and clinical significance
Downstream the signalling runs through PI3K/AKT and MAPK/ERK, which is why phospho-AKT and phospho-ERK are the near-universal readouts
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A washout period of at least several weeks is advisable, though specific recommendations cannot be made given limited data
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