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This dose is maintained for at least four weeks to allow the body to adapt to the medication and to minimize gastrointestinal side effects
Importantly, clinical studies typically have indiscriminately tested interventions and have rarely utilised biomarkers or clinical symptoms to identify treatment responders, so the clinical indications are in some cases based on the authors opinion regarding the rationalisation of different management options
Semaglutide is a biologic peptide produced using recombinant DNA technology, a far more complex process than manufacturing a standard chemical compound
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