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Name: surmount-1 trial tirzepatide weight loss non-diabetic Flow of Participants in the SURMOUNT-4 aIncludes 10 individuals Effect of tirzepatide in SURMOUNT-1
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The authors themselves note that experimental validation is required

Key points Leg cramps (especially calves and feet) are most commonly reported Nighttime cramps and post-exercise cramps appear most frequently Duration typically ranges from seconds to minutes per episode Intensity varies from mild discomfort to painful spasms that wake patients from sleep Managing muscle cramps Most Mounjaro-related muscle cramps can be effectively managed with simple strategies

Toxicol Appl Pharmacol 242 ,241-246 (2010)