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Abnormal sperm morphology and an increase in malondialdehyde (MDA) levels were observed in the 10 mg/kg treatment group, whereas the changes were more pronounced in the 20 mg/kg treatment group, which exhibited a decrease in sperm counts, abnormal sperm morphology, DNA damage, degradation of cellular tubular structures, and elevated serum LH and testosterone levels

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Neuropediatrics (2007) 38:17983.10.1055/s-2007-991148 97 Perez-DuenasBOrmazabalATomaCTorricoBCormandBSerranoMet alCerebral folate deficiency syndromes in childhood: clinical, analytical, and etiologic aspects

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