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As discussed above, DPP-4 levels are positively correlated with BMI and insulin resistance and, in some studies, also to glycaemic control, but the mechanisms regulating synthesis and release of DPP-4 are still incompletely understood
As described in the release from Lilly, detailed TRIUMPH-4 results will be presented at a future medical meeting and published in a peer-reviewed journal, and additional results from the TRIUMPH program including a 4 mg maintenance dose are expected in 2026
They regulate key biological processes such as inflammation, cellular migration, proliferation, and angiogenesis [19, 20]
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