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In the IFIGENIA study, adding NAC 600 mg/day to prednisone and azathioprine slowed lung function decline and improved Diffusing Capacity of the Lung for Carbon Monoxide (DLCO), especially in early IPF (136, 137)
While they share some overlapping areas of investigation, they differ significantly in structure, origin, and proposed mechanisms
Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y et al (2022) Cepharanthine attenuates early brain injury after subarachnoid hemorrhage in mice via inhibiting 15-lipoxygenase-1-mediated microglia and endothelial cell ferroptosis
The former should work better for gastrointestinal health support, while the latter might provide a greater level of joint and muscle support
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