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GLP-1RAs are a class of drugs that can activate the GLP-1 receptor and promote its binding to the specific receptor of pancreatic -cells, ultimately improving insulin concentration, inhibiting glucagon secretion, reducing food intake, and delaying gastric emptying (Monami et al., 2014
The Future of Peptide Therapies in Obesity and Metabolic Disease
Dietary fibre, particularly soluble fibre, appears to enhance GLP-1 production by promoting the formation of short-chain fatty acids through bacterial fermentation in the colon, which may then stimulate L-cells
Cai X, She M, Xu M, Chen H, Li J, Chen X, Zheng D, Liu J, Chen S, Zhu J
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