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The Three Amino Acids Necessary for Higher Glutathione Concentrations The three amino acids that are critical for supporting higher glutathione concentrations and assisting with proper function include: Glutamate is the first in the peptide sequence, and its side chain interacts with the cysteine moiety in a somewhat unusual peptide linkage, known as the -glutamyl bond

Autophagy 8:17691781 Cardaci S, Filomeni G, Rotilio G, Ciriolo MR (2010) p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration