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In the presence of compound 2, both GLP-1 and the ECD moved inwards to the TMD core by 0.7 and 1.3 (measured at the C of Y19 in GLP-1 and P90 in ECD), respectively
Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily approved by the FDA for managing type 2 diabetes mellitus and, in some cases, chronic weight management
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Funding This study was supported in part by NIH intramural funding ZIA-DA-000635 (Clinical Psychoneuroendocrinology and Neuropsychopharmacology SectionPI: LL), jointly supported by the NIDA Intramural Research Program and the NIAAA Division of Intramural Clinical and Biological Research (MRL, LL)
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