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Each dose increase may trigger a brief 3- to 5-day nausea recurrence, but this pattern becomes less pronounced with successive increases
Separate-vial protocols require separate math because injection count and vial coverage change
Three, B12 supplementation is used, and the optimal frequency of administration is established in order to stay symptom-free
Daily administration increases the risk of methionine overload, elevated homocysteine, and gastrointestinal side effects without improving fat oxidation beyond what the liver can process
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