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MP: Writing original draft, Methodology, Conceptualization, Validation, Project administration, Supervision, Investigation, Writing review and editing, Data curation
Vascular effects contribute significantly to GHK-Cus healing properties
Results showed that the ingredient significantly increased NAD+ levels in senescent fibroblasts, activated the SIRT1 signaling pathway, reduced the expression of senescence-associated -galactosidase (SA--gal), decreased intracellular reactive oxygen species accumulation, and promoted collagen synthesis
Cancer 89:14401447 Smith PS, Zhao WL, Robbins ME (2007) Inhibiting catalase activity sensitizes 36B10 rat glioma cells to oxidative stress
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