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Unweighted UniFrac distance analysis, reflecting phylogenetic community structure, demonstrated the greatest phylogenetic dissimilarity in the VPA-ASD group relative to controls (Figure S4C)

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This combination is popular for its complementary interaction, where each peptide supports structured and balanced growth-hormone signaling

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Considering that YAP1 binds to HIF1 and maintain its stability 28 , which increases HEXB transcription, our findings depict an HEXB-driven positive feedback loop dependent on YAP1/HIF1 transcription activity

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