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The oxidation steps, utilizing glucose-6-phosphate (G6P) as the substrate, occur at the beginning of the pathway and are the reactions that generate NADPH
In contrast, ascorbic acid (vitamin C) acts only on the outer layer of cell membranes, whereas -carotene or -tocopherol (vitamin E) act on the inner layer 13
All participants were thoroughly briefed on the study and provided written informed consent
In addition to enhancing skin radiance, they also reduce blemishes and improve skin firmness
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