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A specific gut microbiota dysbiosis of type 2 diabetic mice induces GLP-1 resistance through an enteric NO-dependent and gut-brain axis mechanism
TMAO is predominantly sourced from choline (found in foods such as red meat, fish, poultry, and eggs) and metabolized by microbiota to TMA and then to TMAO through the action of the hepatic enzyme, flavin monooxygenase 3 (FMO3) (8)
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